Crispr’s New Frontier

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130 – April, 2025

By Sue M. Copeland

The changes came fast. Your once active Doberman Pinscher opts to nap rather than play. When she tries to follow you around, she pants and coughs. Her legs and paws swell.

You’re worried. Dobermans and other breeds such as Boxers, Cocker Spaniels, and Great Danes (plus their mixed-breed offspring) are prone to a heart-muscle disease called dilated cardiomyopathy (DCM), a progressive condition that can lead to heart failure and often has genetic roots.

An echocardiogram by a canine cardiologist confirms your fear. The cardiologist explains that while medication can help slow DCM’s progression, there is no available cure.

With the DCM diagnosis, your dog joins an estimated 10 percent of all canines in the U.S. who have a form of cardiac disease that can cause heart failure. Fortunately, new approaches in gene editing show promise for treating chronic heart diseases, such as DCM.

SPLICE OF LIFE

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130 – April, 2025

Short URL: http://caninechronicle.com/?p=323104

Posted by AnthonyA on Apr 10 2025. Filed under Current Articles, Featured. You can follow any responses to this entry through the RSS 2.0. Both comments and pings are currently closed.