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New DNA Testing Scheme For American Cocker Spaniels

The Kennel Club has approved a new official DNA test reporting scheme for progressive rod-cone degeneration, progressive retinal atrophy (prcd-PRA) in American Cocker Spaniels following consultation with the breed health co-ordinator.

PRA (progressive retinal atrophy) is a condition that causes the parts of the eye that are sensitive to light to break down. PRA produces a gradual loss of vision in both eyes, eventually leading to total blindness. In prcd-PRA the parts of the eye that work in low-light, known as rod cells, begin to degenerate first, followed by a deterioration of the parts of the eye that deal with bright light, known as cone cells. A number of breeds are affected by PRA, and although the clinical effects are usually the same, each breed’s version of PRA is often caused by a different genetic mutation.

prcd-PRA is described as an autosomal-recessive condition. This means that a dog must inherit two copies of an abnormal gene (one from its mother and one from its father) before its health is likely to be affected. A dog that inherits only one copy of the abnormal gene (from its mother or its father) will likely have no signs of the disease, but will be a carrier and may pass the gene on to any offspring.

Tested dogs will be recorded on the Kennel Club systems as either:

Clear

The dog does not have any copies of the abnormal gene associated with the disease. The dog is highly unlikely to be clinically affected and will only pass on a normal copy of the gene to a puppy.

Carrier

The dog has one copy of the normal gene and one copy of the abnormal gene associated with the disease. The dog is highly unlikely to be clinically affected, but may pass one copy of the normal gene, or one copy of the abnormal gene on to a puppy.

Affected

The dog has two copies of the abnormal gene associated with the disease. The dog will likely be clinically affected by the disorder and will pass one copy of the abnormal gene on to any potential offspring.

To find out which laboratories the Kennel Club is able to record results from, and which labs will send results direct to the Kennel Club, please refer to the worldwide DNA testing list at www.thekennelclub.org.uk/worldwide-dna-tests. Please note that this listing is not necessarily comprehensive and other labs may offer the tests.

The Kennel Club constantly reviews DNA testing schemes in conjunction with breed clubs to ensure that breeders are supported with resources which help them to make responsible breeding decisions. The Kennel Club works alongside breed clubs and breed health coordinators in a collaborative effort to improve the health of pedigree dogs and is happy to consider a club’s request to add a new DNA test to its lists. A formal request from the breed health coordinator or a majority request from the breed clubs is normally required to do this.

Test results will be added to the dog’s registration details which will trigger the publication of the result in the next available Breed Records Supplement. The result will appear on any new registration certificate issued for the dog and on the registration certificates of any future progeny of the dog, and also on the Health Test Results Finder on the Kennel Club website.

Results for dogs already tested can also be recorded, but owners will need to submit copies of the DNA certificates themselves.  DNA test certificates should be scanned and emailed to health.results@thekennelclub.org.uk.

Owners are reminded that from August 2018, it is mandatory that the dog’s microchip (or tattoo) is recorded along with either the dog’s registered name or registered number on any DNA certificates. Any test results issued after that date that do not carry these identifying features will not be accepted.

Short URL: http://caninechronicle.com/?p=189032

Posted by on Aug 18 2020. Filed under World News. You can follow any responses to this entry through the RSS 2.0. Both comments and pings are currently closed.

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